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Form of workThis position is available to Northeastern University students who are currently enrolled and eligible for Co-op January 2024 - June 2024.
The Computational Sciences Department at The Jackson Laboratory is looking for motivated students interested in advanced bioinformatics and biomedical software development for cutting-edge research focused on improving human health.
You will be working with a small and dedicated team to identify the most accurate genome to use for transcript alignment to genetically diverse mouse genomes. This is important for accurate estimation of transcript and gene abundance and has implications for RNA-sequencing read alignment in other model organisms, as well as humans. This project will focus on improving the alignment of RNA-sequencing to genetically diverse genomes. The incumbent will learn to work with genome sequences and annotation, analyze RNA-sequencing data, and build analysis pipelines using bash and R.
Key Responsibilities
Expected Outcomes
Desired Qualifications
JAX encourages application from a diverse mix of educational experiences and backgrounds. Preferred qualifications for this project include:
Applicants should be:
This position is fully remote. To stay well-connected and on track, you will be expected to meet with your supervisor several times per week.
Please include a resume and cover letter to be considered for this role.
About JAX:
The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org.
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
The Computational Sciences Department at The Jackson Laboratory is looking for motivated students interested in advanced bioinformatics and biomedical software development for cutting-edge research focused on improving human health.
You will be working with a small and dedicated team to identify the most accurate genome to use for transcript alignment to genetically diverse mouse genomes. This is important for accurate estimation of transcript and gene abundance and has implications for RNA-sequencing read alignment in other model organisms, as well as humans. This project will focus on improving the alignment of RNA-sequencing to genetically diverse genomes. The incumbent will learn to work with genome sequences and annotation, analyze RNA-sequencing data, and build analysis pipelines using bash and R.
Key Responsibilities
- Work with a small team under the direction of a Senior Computational Scientist,
- Evaluate the transcript annotation of different genome assemblies
- Align RNA-sequencing data sets to several different genome assemblies
- Assess the quality of the alignments, and
- Compare the alignment quality between genomes
- Ideally, produce a publication describing your results
Expected Outcomes
- experience working in a highly productive, data science environment,
- exposure to leading-edge methods and technologies utilized in advanced biotech enterprises,
- experience with genome assemblies and gene annotation,
- experience with RNA-sequencing alignment and analysis,
- an understanding of the potential career opportunities at JAX and in the field,
- authorship of a scientific publication.
Desired Qualifications
JAX encourages application from a diverse mix of educational experiences and backgrounds. Preferred qualifications for this project include:
- Minimum 3.0 GPA.
- Graduate student in Data Science or Bioinformatics programs.
- competence in bash (variables, loops, flow control statements), and
- R (programming language),
- familiarity with basic biology and genetics, and
- some experience with bioinformatics.
Applicants should be:
- able to demonstrate successful completion of coursework in the related field(s),
- motivated, enthusiastic, and willing to learn,
- able to solve problems independently and to ask for help when needed,
- experienced in working on projects with a team, and
- responsible, reliable, accountable, attentive to detail and quality.
This position is fully remote. To stay well-connected and on track, you will be expected to meet with your supervisor several times per week.
Please include a resume and cover letter to be considered for this role.
About JAX:
The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org.
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
