Associate Scientist Protein Expression

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents. We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

We are seeking a scientist with relevant cell culture and Protein Expression experience to join the Protein Science group in the Discovery Biotherapeutics department at our new state-of-the-art facility in Cambridge, MA. The qualified candidate will be responsible for mammalian expression of proteins in shake flasks and will play a role in support of the biotherapeutic discovery efforts at BMS.

The Discovery Biotherapeutics group supports programs across all BMS therapeutic areas including Oncology, Immunoscience, Cardiovascular Disease, and Fibrosis. Group activities comprise of Protein Expression, purification and characterization making use of high throughput methods and automation to enhance productivity where possible.

Responsibilities:

• Routine maintenance and cell banking of HEK and CHO cells
• Mammalian Protein Expression in shake flasks using both transient transfection and stable cell lines (Expi293, ExpiCHO, CHOZN)
• Harvest of cell culture using filtration and centrifugation
• Antibody purification and quantitation using Blitz or Octet
• Assist with liquid handling and automation method development experiments for miniscale expression.
• On occasion, operation of integrated automation robots to perform small scale expression and purification.
• Ensure accurate registration of protein lots and associated data into Genedata system.
• Maintain a complete and current Electronic Laboratory Notebook.
• Collaborate in multi-disciplinary drug discovery teams, communicate results both written and verbally with matrixed working group.
• Accomplish goals under project team timelines.
• DNA Inventory tracking and maintenance.

Basic Qualifications:

• Bachelor's Degree in Biology, Engineering, or a related field and 2+ years of academic / industry experience

Preferred Qualifications:

• Experience with Mammalian cell culture and aseptic technique is required.
• Experience with Genedata and ELN is highly desirable.
• Must be detail oriented and able to follow protocols effectively.
• Excellent time management skills and a demonstrated ability to work in a team environment.
• Excellent interpersonal and communication skills along with a sense of urgency and ability to work under tight deadlines.
• Experience with liquid handling is desirable.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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