Associate Director, Medicinal Chemistry - Remote

An exceptional opportunity awaits you to become an integral part of our team in a rapidly expanding startup. Join DeepCure and play a pivotal role in reshaping the landscape of drug discovery. We are on the lookout for a dynamic and innovative thinker to join our Discovery team. As a Medicinal Chemist, you will be at the forefront of leveraging our groundbreaking Artificial Intelligence (AI) platform to uncover revolutionary therapeutics. Your role will involve collaborating closely with our drug discovery and machine learning scientists to propel therapeutic targets from proof of concept to candidate selection. A proven track record in drug discovery is essential, and the ability to thrive in a dynamic startup environment is crucial.

This position demands individuals with a comprehensive understanding of the interdisciplinary drug discovery process, coupled with strong managerial and organizational skills within an outsourced setting. Moreover, you should excel in a multidisciplinary environment, serving as a key leader with a keen focus on people management, critical organizational decision-making, and overall team integration. Seize this unique opportunity to take a leading role in revolutionizing the approach to drug discovery within the industry.

More About DeepCure:

Established by a group of researchers from the MIT Media Lab, DeepCure is at the forefront of developing groundbreaking Artificial Intelligence to transform pharmaceutical discovery. Our mission is centered on providing patients with safer and more effective therapeutics, ones highly improbable to be uncovered by any current drug discovery pipeline. DeepCure is reshaping the landscape of drug discovery by seamlessly integrating state-of-the-art Deep Learning algorithms with our unparalleled molecular database and a distinctive approach to experimental data generation.

In this role, you will:

• Devise, implement, and carry out strategic Medicinal Chemistry plans across multiple CROs to enhance efficacy, ADME/DMPK, and safety profiles, aligning with ambitious milestones.
• Collaboratively lead an interdisciplinary project team and deliver timely, well-organized reports to key stakeholders both within and beyond DeepCure
• Formulate and implement strategies for safeguarding and expanding intellectual property while exploring innovative approaches for expanding chemical space.
• Engage proactively in the identification of new therapeutic targets and contribute to the expansion of DeepCure's discovery portfolio by offering insights into target chemical biology and structural biology, facilitating their translation into machine learning models.
• Efficiently collaborate with the leadership team, departmental managers, and various functions, making substantial scientific contributions that significantly influence the company's research direction.
• Take proactive steps to explore novel or alternative technologies to enhance the efficiency of the drug discovery process.

For the right candidate, we'll offer a competitive salary plus equity. Your compensation is rounded out by a strong benefits package:

• A leadership team that values and prioritizes your professional development.
• Flexible work hours
• Unlimited paid leave and sick time
• 401k plan with 5% employer matching.
• Healthcare plans that are fully covered by the employer for you, and mostly covered for your dependents.
• Vision, dental and life insurance plans for you and your dependents.
• Employer participation to FSA (Flexible spending account) for qualified medical expenses
• Commuter benefit for public transportation/ paid parking.
• Work in a cool and vibrant space at the heart of Boston.
• Snacks and drinks in the office.
• Fun socializing events for local and remote team members.

“Brainstorming on my challenges with all these amazing brains deserves a shout-out every sprint” (Jon, a Member of our Platform-Research team).

Most importantly, you'll have a huge impact, do important work, and work with a team of people you'll genuinely enjoy spending the day with.

DeepCure is an equal opportunity employer, dedicated to creating a workplace that is free of harassment and discrimination. We base our employment decisions on business needs, job requirements, and qualifications — that's all. We do not discriminate based on race, gender, religion, health, personal beliefs, age, family or parental status, or any other status. We don't tolerate any kind of discrimination or bias, and we are looking for teammates who feel the same way.

Transparency in coverage policy.

A note to the recruitment community:

We appreciate your interest in our company and the opportunities we offer. Currently, we kindly request that recruiters and agencies refrain from reaching out regarding the Associate Director of Medicinal Chemistry position. Our team is actively engaged in the current recruitment process, and we are not seeking external assistance at this time.

Basic Requirements:

• Doctoral degree (Ph.D.) or equivalent experience in synthetic organic chemistry or Medicinal Chemistry
• 8+ years of experience in the pharmaceutical industry with a track record of scientific innovation and demonstrated success in advancing programs.
• Expert in Medicinal Chemistry with a strong grasp of biology, pharmacology, DMPK, and toxicology. Proficient in integrating data from these disciplines resulting in the creation of high-quality, novel chemical compounds through thoughtful design strategies.
• Extensive background in executing drug discovery programs through an outsourced, CRO-driven model, including the establishment and management of collaborations with CROs, industry partners, and academic institutions.
• A strong patent and publication record evidencing scientific curiosity and strong communication skills.

Preferred Requirements:

• Passionate about the vision and mission of DeepCure to revolutionize drug discovery by challenging conventional processes.
• A natural leader with the ability to motivate and inspire others with a proven track record in effectively leading Medicinal Chemistry and drug discovery programs.
• An expert in modern organic chemistry, coupled with a keen enthusiasm for innovation in synthesis and automation.
• Specialized in small molecule development, spanning from hit identification to candidate selection, and brings a broad understanding of other fields such as structural biology and chemical biology.
• Excited to incorporate advanced computational tools and help develop the next generation of AI workflows.
• Adept at effective management across diverse time zones and cultures with a demonstrated ability to thrive in cross-functional teams, emphasizing teamwork, collaboration, and communication.
• Comfortable in an intentionally flat organization where we reward talent density and provide an opportunity to truly define your own career path through ideation and execution.
• Able to influence without authority and utilize the team to advance the company mission in an organic way and make it happen.
• Is not scared to jump in and figure things out and the uncertainty of not knowing if an idea will work as hypothesized.