Research Associate I- Proteomics

Job Description

The Proteomics Group (Carr Lab) at the Broad Institute of MIT and Harvard is looking for a highly motivated research associate to become part of a team that develops and applies state-of-the art proteomics technology to address compelling questions in biology, chemistry and clinical medicine with a focus on immunology. The specific research areas that this research associate will participate in include the following:

• Using mass spectrometry techniques to improve our understanding of immune biology and help aid the development of personalized immunotherapies
• Studying the rules that govern how cells present HLA molecules and associated antigens to the immune system by applying mass spectrometry based assays
• Implementing novel HLA associated peptide profiling workflows to study neoantigens and other disease antigen targets of high biological or clinical interest in cancer, autoimmune and infectious diseases
• Working closely with collaborators focused on immunology throughout the Broad Institute community including Harvard, MIT and Harvard-affiliated hospitals

Successful candidates will work in one or more of these areas together with an interdisciplinary team of clinicians, biologists, computational and proteomics scientists to deeply characterize and understand the immunopeptidomes and proteomes of tumor-derived material, cells and biofluids. The Broad Institute is a world-leading non-profit research organization dedicated to realizing the promise of the post-genomic era for human benefit. Located in Cambridge, MA with strong ties to MIT, Harvard, and world class Boston hospitals, the Broad Institute brings together scientists of diverse backgrounds to solve critical problems in biology and medicine in an interdisciplinary manner.

The Broad Institute, and the embedded Proteomics Group (www.broadinstitute.org/proteomics), have an outstanding track-record in training the next generation of research scientists and in developing and applying proteomic technologies critical to address important questions in biology and medicine. We collaborate with top-level researchers throughout the world, and results of these studies and our technology developments are published in top-tier journals. Qualifications Candidates must have:

• Bachelor's degree
• Majored in any life science (including neuroscience), chemistry, bioengineering, biochemistry, chemical engineering, or something similar
• Undergraduate research experience, including working familiarity with basic laboratory techniques and principles of molecular biology preferred
• Exceptional organizational skills, critical thinking skills, and attention to details
• Excellent communication skills and ability to interact professionally with all levels of staff and external contacts
• Ability to work independently in response to guidance and direction and as part of a team
• Ability to exercise judgment within defined practices, techniques, and standard operating procedures
• Desire and willingness to learn, develop, and execute new assays or lab techniques
• Interest in staying with the Broad for at least two years

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

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