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Form of workAs an organization whose mission is to translate science into global public health impact, working on vaccines and therapeutics, IAVI has a vaccine policy which states that subject to applicable law, we require all U.S. and Puerto Rico based employees to be vaccinated for COVID-19, unless they have an approved medical or religious exemption or accommodation. We are committed to supporting our employees during this process as we work to ensure a safe and healthy work environment.
Position Description
Job Title: Research Associate I
Location: Neutralizing Antibody Center (NAC), La Jolla, CA
Reports to: Principal Scientist, AMR Immunotherapeutics
Job Summary:
IAVI's Neutralizing Antibody Center in La Jolla, CA is seeking an ambitious Research Associate who shares in IAVI's mission to translate science into global health impact! The Research Associate supports and partners with senior research associates, postdoctoral associates, and scientists of the antimicrobial resistance (AMR) team, developing effective antibody interventions for the purpose of combatting antimicrobial resistant infections in low- and middle- income countries. The Research Associate joins an ongoing collaborative effort to discover and engineer antibodies with bactericidal and/or neutralizing activity against enteric bacterial pathogens such as Shigella. The Research Associate is responsible for reagent production, high-throughput serum bactericidal assays, antibody isolation and characterization, routine cell-culture, and bacterial virulence assays.
Key Responsibilities:
Education and Work Experience:
Qualifications and Skills:
Organizational Overview:
IAVI is a nonprofit scientific research organization dedicated to addressing urgent, unmet global health challenges including HIV and tuberculosis. Our mission is to translate scientific discoveries into affordable, globally accessible public health solutions. Through scientific and clinical research in Africa, India, Europe, and the U.S., IAVI is pioneering the development of biomedical innovations designed for broad global access. We develop vaccines and antibodies in and for the developing world and seek to accelerate their introduction in low-income countries. IAVI programs and partnerships are grounded in the regions of the world where the disease burden is the greatest, and our approach emphasizes sustainability. Our network of clinical research center partners in Africa and India helps strengthen in-country research capacity and supports the training and education of the next generation of scientists. The global impact of our science includes fundamental contributions to understanding the biology of HIV infection, which IAVI and others are applying toward advancing vaccine science and immunology. IAVI accelerates scientific discovery and development by fostering unique collaborations among academia, industry, local communities, governments, and funders to explore new and better ways to address public health threats that disproportionately affect people living in poverty. Our global reach, including a clinical research network in five countries in sub-Saharan Africa and in India, has allowed us to make fundamental contributions to understanding the epidemiology, transmission, virology, and immunology of HIV. This work played a key role in facilitating the design of promising HIV vaccine candidates, as well as the discovery of broadly neutralizing antibodies that are now being advanced as promising approaches for HIV prevention. Our integrated capabilities in vaccine and antibody discovery, development, and clinical research take advantage of bio-pharmaceutical industry expertise to accelerate the development and testing of prevention methods for HIV and other diseases. Through the Product Development Center, we support external researchers with technical and scientific expertise to accelerate the development of their own products.
About the NAC:
IAVI's Neutralizing Antibody Center (NAC) was established in 2002 at Scripps Research in La Jolla, CA, and today, is a leading source of innovation in the study of broadly neutralizing antibodies (bnAbs) and the design of immunogens to elicit these antibodies through vaccination. The NAC brings together leading investigators - including structural and computational biologists, immunologists, protein chemists, and glycobiologists - from institutions worldwide.
IAVI CORE VALUES:
Disclaimer: Nothing in this job description restricts management's right to assign or reassign duties and responsibilities to this job at any time. The above statements are intended to describe the general nature and level of work being performed by individuals assigned to this position. They are not intended to be an exhaustive list of all duties, responsibilities and skills required of personnel so classified. This document does not create an employment contract, implied or otherwise, other than an "at-will" relationship. IAVI is an equal opportunity employer and applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
IAVI IS AN EQUAL OPPORTUNITY EMPLOYER actively committed to fostering a diverse and inclusive global organization. IAVI believes that diversity and inclusion among our teammates is critical, and we seek to recruit, develop and retain the most talented people from a representative candidate pool. At IAVI, we celebrate the spectrum of colleagues' experiences and believe that dedication to our mission above all is essential to our success as a scientific global non-profit. IAVI upholds these principles through IAVI's Global Diversity and Inclusion Committee.
IAVI has zero tolerance for discrimination or harassment on the basis of race, color, ethnicity, caste, national origin, home language, ancestry, religion, marital or civil partnership status, age, physical or mental disability, HIV status and any other medical condition, genetic information, pregnancy, sexual orientation, gender identity or expression, and veteran status, in addition to any other status protected under the law in any of our locations worldwide.
Compensation and Benefits Information for US-Based Candidates:
The annual base salary for this position is targeted at $50,000.00 - 60,000.00, with some variation based on experience level. In addition, this position offers competitive benefits such as annual bonus, generous retirement savings plan, three health insurance plans to choose from, and other benefits.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor's legal duty to furnish information. 41 CFR 60-1.35(c)
Position Description
Job Title: Research Associate I
Location: Neutralizing Antibody Center (NAC), La Jolla, CA
Reports to: Principal Scientist, AMR Immunotherapeutics
Job Summary:
IAVI's Neutralizing Antibody Center in La Jolla, CA is seeking an ambitious Research Associate who shares in IAVI's mission to translate science into global health impact! The Research Associate supports and partners with senior research associates, postdoctoral associates, and scientists of the antimicrobial resistance (AMR) team, developing effective antibody interventions for the purpose of combatting antimicrobial resistant infections in low- and middle- income countries. The Research Associate joins an ongoing collaborative effort to discover and engineer antibodies with bactericidal and/or neutralizing activity against enteric bacterial pathogens such as Shigella. The Research Associate is responsible for reagent production, high-throughput serum bactericidal assays, antibody isolation and characterization, routine cell-culture, and bacterial virulence assays.
Key Responsibilities:
- Perform routine bacterial, yeast, and mammalian cell culture with minimal supervision.
- Assist in production and isolation of reagents such as antibodies, lipopolysaccharide, and outer membrane vesicles from mammalian, yeast, and bacterial production systems.
- With support, assist in the biochemical characterization of antibodies and other proteins.
- Independently evaluate lead antibody candidates by conducting effector function assays and Shigella virulence assays.
- Assist with setup and operation of cell sorters for antigen-specific single cell sorting.
Education and Work Experience:
- A Bachelor's degree in the Biological Sciences or a related field is required;
- Experience in laboratory work related to biochemistry, immunology, or microbiology (protein production, molecular cloning, ELISAs, bacterial transformation) is desirable.
Qualifications and Skills:
- Knowledge of Good standard laboratory safety practices and the willingness to work with BSL2 pathogens or other potentially infectious samples is highly preferred.
- Excellent communication skills, including presenting data at internal meetings, and the ability to read, understand, and discuss relevant literature with co-workers is desirable.
- Demonstrable time management skills, including the ability to prioritize short-term and long-term workloads and work both independently and as a team member is highly desirable.
- In-depth understanding of the entire MS Office suite is desirable.
- Prior experience with experimental design, data handling, and statistical analysis is an highly preferred.
- Cultural sensitivity and respect for diverse colleagues
- Motivated by and committed to IAVI's mission of translating science into global health impact.
Organizational Overview:
IAVI is a nonprofit scientific research organization dedicated to addressing urgent, unmet global health challenges including HIV and tuberculosis. Our mission is to translate scientific discoveries into affordable, globally accessible public health solutions. Through scientific and clinical research in Africa, India, Europe, and the U.S., IAVI is pioneering the development of biomedical innovations designed for broad global access. We develop vaccines and antibodies in and for the developing world and seek to accelerate their introduction in low-income countries. IAVI programs and partnerships are grounded in the regions of the world where the disease burden is the greatest, and our approach emphasizes sustainability. Our network of clinical research center partners in Africa and India helps strengthen in-country research capacity and supports the training and education of the next generation of scientists. The global impact of our science includes fundamental contributions to understanding the biology of HIV infection, which IAVI and others are applying toward advancing vaccine science and immunology. IAVI accelerates scientific discovery and development by fostering unique collaborations among academia, industry, local communities, governments, and funders to explore new and better ways to address public health threats that disproportionately affect people living in poverty. Our global reach, including a clinical research network in five countries in sub-Saharan Africa and in India, has allowed us to make fundamental contributions to understanding the epidemiology, transmission, virology, and immunology of HIV. This work played a key role in facilitating the design of promising HIV vaccine candidates, as well as the discovery of broadly neutralizing antibodies that are now being advanced as promising approaches for HIV prevention. Our integrated capabilities in vaccine and antibody discovery, development, and clinical research take advantage of bio-pharmaceutical industry expertise to accelerate the development and testing of prevention methods for HIV and other diseases. Through the Product Development Center, we support external researchers with technical and scientific expertise to accelerate the development of their own products.
About the NAC:
IAVI's Neutralizing Antibody Center (NAC) was established in 2002 at Scripps Research in La Jolla, CA, and today, is a leading source of innovation in the study of broadly neutralizing antibodies (bnAbs) and the design of immunogens to elicit these antibodies through vaccination. The NAC brings together leading investigators - including structural and computational biologists, immunologists, protein chemists, and glycobiologists - from institutions worldwide.
IAVI CORE VALUES:
- Dedication to the Mission: We are committed to the translation of scientific discoveries into affordable, globally accessible public health solutions.
- Innovative Evolution: We are committed to solving complex problems in creative and innovative ways, learning from our mistakes and successes and never giving up
- Integrity: We are committed to meeting the highest ethical and professional standards in everything we do and to taking responsibility for our actions to earn respect
- Collaboration: We are committed to embracing diversity, the power of global teamwork and the belief that by working as one we can make a difference
Disclaimer: Nothing in this job description restricts management's right to assign or reassign duties and responsibilities to this job at any time. The above statements are intended to describe the general nature and level of work being performed by individuals assigned to this position. They are not intended to be an exhaustive list of all duties, responsibilities and skills required of personnel so classified. This document does not create an employment contract, implied or otherwise, other than an "at-will" relationship. IAVI is an equal opportunity employer and applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
IAVI IS AN EQUAL OPPORTUNITY EMPLOYER actively committed to fostering a diverse and inclusive global organization. IAVI believes that diversity and inclusion among our teammates is critical, and we seek to recruit, develop and retain the most talented people from a representative candidate pool. At IAVI, we celebrate the spectrum of colleagues' experiences and believe that dedication to our mission above all is essential to our success as a scientific global non-profit. IAVI upholds these principles through IAVI's Global Diversity and Inclusion Committee.
IAVI has zero tolerance for discrimination or harassment on the basis of race, color, ethnicity, caste, national origin, home language, ancestry, religion, marital or civil partnership status, age, physical or mental disability, HIV status and any other medical condition, genetic information, pregnancy, sexual orientation, gender identity or expression, and veteran status, in addition to any other status protected under the law in any of our locations worldwide.
Compensation and Benefits Information for US-Based Candidates:
The annual base salary for this position is targeted at $50,000.00 - 60,000.00, with some variation based on experience level. In addition, this position offers competitive benefits such as annual bonus, generous retirement savings plan, three health insurance plans to choose from, and other benefits.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor's legal duty to furnish information. 41 CFR 60-1.35(c)
